Zwei neue Dammaran-Sapogenine aus den Blättern von Panax notoginseng

Wei Junxian; Chang Liangyu; Wang Jufen; Edmund Friedrichs; Monika Jores; Heinrich Puff; Chen-Wei-shin; Eberhard Breitmaier

doi:10.1055/s-2007-971367

Planta Med 1982; 45(7): 167-171
DOI: 10.1055/s-2007-971367

Research Articles

Zwei neue Dammaran-Sapogenine aus den Blättern von Panax notoginseng

Two New Dammaran Sapogenins from Leaves of Panax notoginsengWei Junxian¹ , Chang Liangyu¹ , Wang Jufen¹ , Edmund Friedrichs² , Monika Jores² , Heinrich Puff² , Chen-Wei-shin³ , Eberhard Breitmaier³

¹Yunnan Institute of Materia Medica, Kunming, VR China
²Institut für Anorganische Chemie der Universität Bonn, Bonn, Federal Republic of Germany
³Institut für Organische Chemie und Biochemie der Universität Bonn, Bonn, Federal Republic of Germany

Abstract

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Abstract

Hydrolysis of the crude saponin extracted from the leaves of Panax notoginseng (BURK.) F. H. CHEN yields five sapogenins which are separated by column chromatography. Two of these are identified to be panaxadiol and panaxatriol whose structures were elucidated earlier. The third sapogenin ist found to be Dammar-20(22)en-3β, 12β,-26-triol by carbon-13 NMR. The structure of the fourth sapogenin is established by X-ray diffractometry and carbon-13 NMR to be 20 (R)-Dammaran-3β, 12β, 20, 25-tetrol.

Key Word Index

Panax notoginseng - Araliaceae - Dammarane sapogenins - Dammar-20(22)en-3β, 12β, 26-triol - 20 (R)-Dammaran-3β, 12β, 20, 25-tetrol - Panaxadiol - Panaxatriol - Triterpenes, tetracyclic

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